PUBLICATIONS研究業績

Hypocretin/orexin neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice

Yang L, Zou B, Xiong X, Pascual C, Xie J, Malik A, Xie J, Sakurai T, Xie XS.

J Neurosci. 2013 Mar 20;33(12):5275-84. doi: 10.1523/JNEUROSCI.3200-12.2013.

VIEW MORE

Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice

Tsuneki H, Tokai E, Sugawara C, Wada T, Sakurai T, Sasaoka T.

Neuropeptides. 2013 Jun;47(3):213-9. doi: 10.1016/j.npep.2013.02.002. Epub 2013 Mar 16.

VIEW MORE

Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation

Xiong X, White RE, Xu L, Yang L, Sun X, Zou B, Pascual C, Sakurai T, Giffard RG, Xie XS.

Stroke. 2013 Mar;44(3):764-70. doi: 10.1161/STROKEAHA.112.681700. Epub 2013 Jan 24.

VIEW MORE

Optogenetic probing of fast glutamatergic transmission from hypocretin/orexin to histamine neurons in situ

Schöne C, Cao ZF, Apergis-Schoute J, Adamantidis A, Sakurai T, Burdakov D.

J Neurosci. 2012 Sep 5;32(36):12437-43. doi: 10.1523/JNEUROSCI.0706-12.2012.

VIEW MORE

A single nucleotide polymorphism of the neuropeptide B/W receptor-1 gene influences the evaluation of facial expressions

Watanabe N, Wada M, Irukayama-Tomobe Y, Ogata Y, Tsujino N, Suzuki M, Furutani N, Sakurai T, Yamamoto M.

PLoS One. 2012;7(4):e35390. doi: 10.1371/journal.pone.0035390. Epub 2012 Apr 24.

VIEW MORE

[Connectomics of orexin-producing neurons: analysis using mouse models]

Sakurai T.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2011 Nov;31(5-6):223-9.

Bmal1 in the nervous system is essential for normal adaptation of circadian locomotor activity and food intake to periodic feeding

Mieda M, Sakurai T.

J Neurosci. 2011 Oct 26;31(43):15391-6. doi: 10.1523/JNEUROSCI.2801-11.2011.

VIEW MORE

Orexin neurons receive glycinergic innervations

Hondo M, Furutani N, Yamasaki M, Watanabe M, Sakurai T.

PLoS One. 2011;6(9):e25076. doi: 10.1371/journal.pone.0025076. Epub 2011 Sep 16.

VIEW MORE

Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice

Sasaki K, Suzuki M, Mieda M, Tsujino N, Roth B, Sakurai T.

PLoS One. 2011;6(5):e20360. doi: 10.1371/journal.pone.0020360. Epub 2011 May 27.

VIEW MORE

Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

Sakurai T, Mieda M.

Trends Pharmacol Sci. 2011 Aug;32(8):451-62. doi: 10.1016/j.tips.2011.03.007. Epub 2011 May 11.

VIEW MORE

Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep

Mieda M, Hasegawa E, Kisanuki YY, Sinton CM, Yanagisawa M, Sakurai T.

J Neurosci. 2011 Apr 27;31(17):6518-26. doi: 10.1523/JNEUROSCI.6506-10.2011.

VIEW MORE

Orexin gene transfer into zona incerta neurons suppresses muscle paralysis in narcoleptic mice

Liu M, Blanco-Centurion C, Konadhode R, Begum S, Pelluru D, Gerashchenko D, Sakurai T, Yanagisawa M, van den Pol AN, Shiromani PJ.

J Neurosci. 2011 Apr 20;31(16):6028-40. doi: 10.1523/JNEUROSCI.6069-10.2011.

VIEW MORE

Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory

Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T.

PLoS One. 2011 Feb 24;6(2):e16972. doi: 10.1371/journal.pone.0016972.

VIEW MORE

Decreased intake of sucrose solutions in orexin knockout mice

Matsuo E, Mochizuki A, Nakayama K, Nakamura S, Yamamoto T, Shioda S, Sakurai T, Yanagisawa M, Shiuchi T, Minokoshi Y, Inoue T.

J Mol Neurosci. 2011 Feb;43(2):217-24. doi: 10.1007/s12031-010-9475-1. Epub 2010 Nov 18.

VIEW MORE

[Orexin (ORX)]

Sakurai T.

Nihon Rinsho. 2010 Jul;68 Suppl 7:633-6.

Orexin neurons are indispensable for stress-induced thermogenesis in mice

Zhang W, Sunanaga J, Takahashi Y, Mori T, Sakurai T, Kanmura Y, Kuwaki T.

J Physiol. 2010 Nov 1;588(Pt 21):4117-29. doi: 10.1113/jphysiol.2010.195099. Epub 2010 Aug 31.

VIEW MORE

Ectopic overexpression of orexin alters sleep/wakefulness states and muscle tone regulation during REM sleep in mice

Willie JT, Takahira H, Shibahara M, Hara J, Nomiyama M, Yanagisawa M, Sakurai T.

J Mol Neurosci. 2011 Feb;43(2):155-61. doi: 10.1007/s12031-010-9437-7. Epub 2010 Aug 14.

VIEW MORE

The orexin system: roles in sleep/wake regulation

Sakurai T, Mieda M, Tsujino N.

Ann N Y Acad Sci. 2010 Jul;1200:149-61. doi: 10.1111/j.1749-6632.2010.05513.x.

VIEW MORE

Activation of bombesin receptor subtype-3 influences activity of orexin neurons by both direct and indirect pathways

Furutani N, Hondo M, Tsujino N, Sakurai T.

J Mol Neurosci. 2010 Sep;42(1):106-11. doi: 10.1007/s12031-010-9382-5. Epub 2010 May 14.

VIEW MORE

Circadian characteristics of mice depleted with GPR7

Uchio N, Doi M, Matsuo M, Yamazaki F, Mizoro Y, Hondo M, Sakurai T, Okamura H.

Biomed Res. 2009 Dec;30(6):357-64. doi: 10.2220/biomedres.30.357.

VIEW MORE