PUBLICATIONS研究業績

Reduced expression of the endothelin receptor type B gene in piebald mice caused by insertion of a retroposon-like element in intron 1

Yamada T, Ohtani S, Sakurai T, Tsuji T, Kunieda T, Yanagisawa M.

J Biol Chem. 2006 Apr 21;281(16):10799-807. doi: 10.1074/jbc.M512618200. Epub 2006 Feb 24.

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Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor

Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M.

Endocrinology. 2006 May;147(5):2306-14. doi: 10.1210/en.2005-1357. Epub 2006 Feb 16.

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Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice

Zhang W, Sakurai T, Fukuda Y, Kuwaki T.

Am J Physiol Regul Integr Comp Physiol. 2006 Jun;290(6):R1654-63. doi: 10.1152/ajpregu.00704.2005. Epub 2006 Jan 12.

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Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine

Narita M, Nagumo Y, Hashimoto S, Narita M, Khotib J, Miyatake M, Sakurai T, Yanagisawa M, Nakamachi T, Shioda S, Suzuki T.

J Neurosci. 2006 Jan 11;26(2):398-405. doi: 10.1523/JNEUROSCI.2761-05.2006.

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Uterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury

Yanagita M, Okuda T, Endo S, Tanaka M, Takahashi K, Sugiyama F, Kunita S, Takahashi S, Fukatsu A, Yanagisawa M, Kita T, Sakurai T.

J Clin Invest. 2006 Jan;116(1):70-9. doi: 10.1172/JCI25445. Epub 2005 Dec 8.

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Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

Crocker A, España RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE.

Neurology. 2005 Oct 25;65(8):1184-8. doi: 10.1212/01.wnl.0000168173.71940.ab. Epub 2005 Sep 14.

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[Orexin]

Sakurai T.

Nihon Rinsho. 2005 Aug;63 Suppl 8:600-2.

Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor

Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T.

J Neurosci. 2005 Aug 10;25(32):7459-69. doi: 10.1523/JNEUROSCI.1193-05.2005.

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Association of an orexin 1 receptor 408Val variant with polydipsia-hyponatremia in schizophrenic subjects

Meerabux J, Iwayama Y, Sakurai T, Ohba H, Toyota T, Yamada K, Nagata R, Irukayama-Tomobe Y, Shimizu H, Yoshitsugu K, Ohta K, Yoshikawa T.

Biol Psychiatry. 2005 Sep 1;58(5):401-7. doi: 10.1016/j.biopsych.2005.04.015.

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Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues

Ikeda Y, Iguchi H, Nakata M, Ioka RX, Tanaka T, Iwasaki S, Magoori K, Takayasu S, Yamamoto TT, Kodama T, Yada T, Sakurai T, Yanagisawa M, Sakai J.

Biochem Biophys Res Commun. 2005 Aug 5;333(3):778-86. doi: 10.1016/j.bbrc.2005.06.005.

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Roles of orexin/hypocretin in regulation of sleep/wakefulness and energy homeostasis

Sakurai T.

Sleep Med Rev. 2005 Aug;9(4):231-41. doi: 10.1016/j.smrv.2004.07.007.

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Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions

Hara J, Yanagisawa M, Sakurai T.

Neurosci Lett. 2005 Jun 3;380(3):239-42. doi: 10.1016/j.neulet.2005.01.046. Epub 2005 Feb 8.

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Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice

Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M.

Neuron. 2005 Apr 21;46(2):297-308. doi: 10.1016/j.neuron.2005.03.010.

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Reverse pharmacology of orexin: from an orphan GPCR to integrative physiology

Sakurai T.

Regul Pept. 2005 Mar 15;126(1-2):3-10. doi: 10.1016/j.regpep.2004.08.006.

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Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, de Lecea L.

J Neurosci. 2004 Dec 15;24(50):11439-48. doi: 10.1523/JNEUROSCI.3459-04.2004.

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Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice

Akiyama M, Yuasa T, Hayasaka N, Horikawa K, Sakurai T, Shibata S.

Eur J Neurosci. 2004 Dec;20(11):3054-62. doi: 10.1111/j.1460-9568.2004.03749.x.

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Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness

Mieda M, Williams SC, Sinton CM, Richardson JA, Sakurai T, Yanagisawa M.

J Neurosci. 2004 Nov 17;24(46):10493-501. doi: 10.1523/JNEUROSCI.3171-04.2004.

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[Regulation of endothelin-1 gene expression]

Hara J, Sakurai T.

Nihon Rinsho. 2004 Sep;62 Suppl 9:591-3.

[Endothelin receptor and intracellular signaling]

Hara J, Sakurai T.

Nihon Rinsho. 2004 Sep;62 Suppl 9:588-90.

Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor

Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T.

J Neurosci. 2004 Aug 11;24(32):7159-66. doi: 10.1523/JNEUROSCI.1027-04.2004.

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