PUBLICATIONS研究業績

ORIGINAL RESEARCH

Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system

Nakamura T, Uramura K, Nambu T, Yada T, Goto K, Yanagisawa M, Sakurai T.

Brain Res. 2000 Aug 4;873(1):181-7. doi: 10.1016/s0006-8993(00)02555-5.

ORIGINAL RESEARCH

Orexins suppress catecholamine synthesis and secretion in cultured PC12 cells

Nanmoku T, Isobe K, Sakurai T, Yamanaka A, Takekoshi K, Kawakami Y, Ishii K, Goto K, Nakai T.

Biochem Biophys Res Commun. 2000 Aug 2;274(2):310-5. doi: 10.1006/bbrc.2000.3137.

ORIGINAL RESEARCH

Subtype-specific trafficking of endothelin receptors

Abe Y, Nakayama K, Yamanaka A, Sakurai T, Goto K.

J Biol Chem. 2000 Mar 24;275(12):8664-71. doi: 10.1074/jbc.275.12.8664.

ORIGINAL RESEARCH

Orexin-induced food intake involves neuropeptide Y pathway

Yamanaka A, Kunii K, Nambu T, Tsujino N, Sakai A, Matsuzaki I, Miwa Y, Goto K, Sakurai T.

Brain Res. 2000 Mar 24;859(2):404-9. doi: 10.1016/s0006-8993(00)02043-6.

ORIGINAL RESEARCH

Endothelin-1 concentration increases in the cerebrospinal fluid in cerebral vasospasm caused by subarachnoid hemorrhage

Suzuki K, Meguro K, Sakurai T, Saitoh Y, Takeuchi S, Nose T.

Surg Neurol. 2000 Feb;53(2):131-5. doi: 10.1016/s0090-3019(99)00179-2.

ORIGINAL RESEARCH

Pathophysiological role of endothelins in pulmonary microcirculatory disorders due to intestinal ischemia and reperfusion

Mitsuoka H, Unno N, Sakurai T, Kaneko H, Suzuki S, Konno H, Terakawa S, Nakamura S.

J Surg Res. 1999 Dec;87(2):143-51. doi: 10.1006/jsre.1999.5694.

ORIGINAL RESEARCH

Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight

Yamanaka A, Sakurai T, Katsumoto T, Yanagisawa M, Goto K.

Brain Res. 1999 Dec 4;849(1-2):248-52. doi: 10.1016/s0006-8993(99)01905-8.

ORIGINAL RESEARCH

Orexins and orexin receptors: implication in feeding behavior

Sakurai T.

Regul Pept. 1999 Nov 30;85(1):25-30. doi: 10.1016/s0167-0115(99)00076-2.

ORIGINAL RESEARCH

Structure, tissue distribution, and pharmacological characterization of Xenopus orexins

Shibahara M, Sakurai T, Nambu T, Takenouchi T, Iwaasa H, Egashira SI, Ihara M, Goto K.

Peptides. 1999;20(10):1169-76. doi: 10.1016/s0196-9781(99)00120-5.

ORIGINAL RESEARCH

Orexins/hypocretins regulate drinking behaviour

Kunii K, Yamanaka A, Nambu T, Matsuzaki I, Goto K, Sakurai T.

Brain Res. 1999 Sep 18;842(1):256-61. doi: 10.1016/s0006-8993(99)01884-3.

ORIGINAL RESEARCH

Structure and function of human prepro-orexin gene

Sakurai T, Moriguchi T, Furuya K, Kajiwara N, Nakamura T, Yanagisawa M, Goto K.

J Biol Chem. 1999 Jun 18;274(25):17771-6. doi: 10.1074/jbc.274.25.17771.

ORIGINAL RESEARCH

Distribution of orexin neurons in the adult rat brain

Nambu T, Sakurai T, Mizukami K, Hosoya Y, Yanagisawa M, Goto K.

Brain Res. 1999 May 8;827(1-2):243-60. doi: 10.1016/s0006-8993(99)01336-0.

ORIGINAL RESEARCH

Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia

Moriguchi T, Sakurai T, Nambu T, Yanagisawa M, Goto K.

Neurosci Lett. 1999 Apr 2;264(1-3):101-4. doi: 10.1016/s0304-3940(99)00177-9.

ORIGINAL RESEARCH

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

Date Y, Ueta Y, Yamashita H, Yamaguchi H, Matsukura S, Kangawa K, Sakurai T, Yanagisawa M, Nakazato M.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):748-53. doi: 10.1073/pnas.96.2.748.

ORIGINAL RESEARCH

Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area

Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK.

J Comp Neurol. 1998 Dec 28;402(4):442-59.

ORIGINAL RESEARCH

Cloning and characterization of a novel endothelin receptor subtype in the avian class

Lecoin L, Sakurai T, Ngo MT, Abe Y, Yanagisawa M, Le Douarin NM.

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3024-9. doi: 10.1073/pnas.95.6.3024.

ORIGINAL RESEARCH

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Mar 6;92(5):1 page following 696. doi: 10.1016/s0092-8674(02)09256-5.

ORIGINAL RESEARCH

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Feb 20;92(4):573-85. doi: 10.1016/s0092-8674(00)80949-6.

ORIGINAL RESEARCH

A novel aortic smooth muscle cell line obtained from p53 knock out mice expresses several differentiation characteristics

Ohmi K, Masuda T, Yamaguchi H, Sakurai T, Kudo Y, Katsuki M, Nonomura Y.

Biochem Biophys Res Commun. 1997 Sep 8;238(1):154-8. doi: 10.1006/bbrc.1997.7218.

ORIGINAL RESEARCH

Role of endothelin-1 in astrocyte responses after acute brain damage

Hama H, Kasuya Y, Sakurai T, Yamada G, Suzuki N, Masaki T, Goto K.

J Neurosci Res. 1997 Mar 15;47(6):590-602. doi: 10.1002/(sici)1097-4547(19970315)47:6<590::aid-jnr4>3.0.co;2-8.