PUBLICATIONS研究業績

Structure, tissue distribution, and pharmacological characterization of Xenopus orexins

Shibahara M, Sakurai T, Nambu T, Takenouchi T, Iwaasa H, Egashira SI, Ihara M, Goto K.

Peptides. 1999;20(10):1169-76. doi: 10.1016/s0196-9781(99)00120-5.

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Orexins/hypocretins regulate drinking behaviour

Kunii K, Yamanaka A, Nambu T, Matsuzaki I, Goto K, Sakurai T.

Brain Res. 1999 Sep 18;842(1):256-61. doi: 10.1016/s0006-8993(99)01884-3.

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Structure and function of human prepro-orexin gene

Sakurai T, Moriguchi T, Furuya K, Kajiwara N, Nakamura T, Yanagisawa M, Goto K.

J Biol Chem. 1999 Jun 18;274(25):17771-6. doi: 10.1074/jbc.274.25.17771.

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Distribution of orexin neurons in the adult rat brain

Nambu T, Sakurai T, Mizukami K, Hosoya Y, Yanagisawa M, Goto K.

Brain Res. 1999 May 8;827(1-2):243-60. doi: 10.1016/s0006-8993(99)01336-0.

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Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia

Moriguchi T, Sakurai T, Nambu T, Yanagisawa M, Goto K.

Neurosci Lett. 1999 Apr 2;264(1-3):101-4. doi: 10.1016/s0304-3940(99)00177-9.

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Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems

Date Y, Ueta Y, Yamashita H, Yamaguchi H, Matsukura S, Kangawa K, Sakurai T, Yanagisawa M, Nakazato M.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):748-53. doi: 10.1073/pnas.96.2.748.

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Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area

Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK.

J Comp Neurol. 1998 Dec 28;402(4):442-59.

Cloning and characterization of a novel endothelin receptor subtype in the avian class

Lecoin L, Sakurai T, Ngo MT, Abe Y, Yanagisawa M, Le Douarin NM.

Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3024-9. doi: 10.1073/pnas.95.6.3024.

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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richarson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Mar 6;92(5):1 page following 696. doi: 10.1016/s0092-8674(02)09256-5.

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Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M.

Cell. 1998 Feb 20;92(4):573-85. doi: 10.1016/s0092-8674(00)80949-6.

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A novel aortic smooth muscle cell line obtained from p53 knock out mice expresses several differentiation characteristics

Ohmi K, Masuda T, Yamaguchi H, Sakurai T, Kudo Y, Katsuki M, Nonomura Y.

Biochem Biophys Res Commun. 1997 Sep 8;238(1):154-8. doi: 10.1006/bbrc.1997.7218.

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Role of endothelin-1 in astrocyte responses after acute brain damage

Hama H, Kasuya Y, Sakurai T, Yamada G, Suzuki N, Masaki T, Goto K.

J Neurosci Res. 1997 Mar 15;47(6):590-602. doi: 10.1002/(sici)1097-4547(19970315)47:6<590::aid-jnr4>3.0.co;2-8.

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Pulmonary hypertension caused by congestive heart failure is ameliorated by long-term application of an endothelin receptor antagonist. Increased expression of endothelin-1 messenger ribonucleic acid and endothelin-1-like immunoreactivity in the lung in congestive heart failure in rats

Sakai S, Miyauchi T, Sakurai T, Yamaguchi I, Kobayashi M, Goto K, Sugishita Y.

J Am Coll Cardiol. 1996 Nov 15;28(6):1580-8. doi: 10.1016/s0735-1097(96)00336-1.

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Anticoagulant factor protein S inhibits the proliferation of rat astrocytes after injury

Tomobe YI, Hama H, Sakurai T, Fujimori A, Abe Y, Goto K.

Neurosci Lett. 1996 Aug 16;214(1):57-60. doi: 10.1016/0304-3940(96)12880-9.

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Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure. Marked increase in endothelin-1 production in the failing heart

Sakai S, Miyauchi T, Sakurai T, Kasuya Y, Ihara M, Yamaguchi I, Goto K, Sugishita Y.

Circulation. 1996 Mar 15;93(6):1214-22. doi: 10.1161/01.cir.93.6.1214.

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Ultraviolet B irradiation increases endothelin-1 and endothelin receptor expression in cultured human keratinocytes

Tsuboi R, Sato C, Oshita Y, Hama H, Sakurai T, Goto K, Ogawa H.

FEBS Lett. 1995 Sep 4;371(2):188-90. doi: 10.1016/0014-5793(95)00912-s.

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Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors

Takigawa M, Sakurai T, Kasuya Y, Abe Y, Masaki T, Goto K.

Eur J Biochem. 1995 Feb 15;228(1):102-8. doi: 10.1111/j.1432-1033.1995.tb20236.x.

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Altered production of endothelin-1 in the hypertrophied rat heart

Sakai S, Yorikane R, Miyauchi T, Sakurai T, Kasuya Y, Yamaguchi I, Sugishita Y, Goto K.

J Cardiovasc Pharmacol. 1995;26 Suppl 3:S452-5.

Endothelin-1-induced downregulation of ETB receptor mRNA: participation of cAMP

Asada S, Kasuya Y, Sakurai T, Masaki T, Goto K.

J Cardiovasc Pharmacol. 1995;26 Suppl 3:S272-5.

Endothelin-1 activates mitogen-activated protein kinases through two independent signalling pathways in rat astrocytes

Kasuya Y, Abe Y, Hama H, Sakurai T, Asada S, Masaki T, Goto K.

Biochem Biophys Res Commun. 1994 Nov 15;204(3):1325-33. doi: 10.1006/bbrc.1994.2608.

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