PUBLICATIONS研究業績
ORIGINAL RESEARCH
Characterization of sleep-wake patterns in a novel transgenic mouse line overexpressing human prepro-orexin/hypocretin
Acta Physiol (Oxf). 2010 Mar;198(3):237-49. doi: 10.1111/j.1748-1716.2009.02068.x. Epub 2009 Dec 10.
ORIGINAL RESEARCH
Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system
Cell Metab. 2009 Dec;10(6):466-80. doi: 10.1016/j.cmet.2009.09.013.
ORIGINAL RESEARCH
Monoaminergic neuronal changes in orexin deficient mice
Neuropharmacology. 2010 Mar-Apr;58(4-5):826-32. doi: 10.1016/j.neuropharm.2009.08.009. Epub 2009 Aug 22.
ORIGINAL RESEARCH
Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states
Acta Physiol (Oxf). 2010 Mar;198(3):287-94. doi: 10.1111/j.1748-1716.2009.02032.x. Epub 2009 Aug 20.
ORIGINAL RESEARCH
Integrative physiology of orexins and orexin receptors
CNS Neurol Disord Drug Targets. 2009 Aug;8(4):281-95. doi: 10.2174/187152709788921663.
ORIGINAL RESEARCH
Attenuated phrenic long-term facilitation in orexin neuron-ablated mice
Respir Physiol Neurobiol. 2009 Sep 30;168(3):295-302. doi: 10.1016/j.resp.2009.07.025. Epub 2009 Aug 5.
ORIGINAL RESEARCH
Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system
Pharmacol Rev. 2009 Jun;61(2):162-76. doi: 10.1124/pr.109.001321.
ORIGINAL RESEARCH
Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis
Brain Res. 2009 Mar 25;1262:25-37. doi: 10.1016/j.brainres.2009.01.022. Epub 2009 Jan 27.
ORIGINAL RESEARCH
Thyrotropin-releasing hormone increases behavioral arousal through modulation of hypocretin/orexin neurons
J Neurosci. 2009 Mar 25;29(12):3705-14. doi: 10.1523/JNEUROSCI.0431-09.2009.
ORIGINAL RESEARCH
Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4459-64. doi: 10.1073/pnas.0811126106. Epub 2009 Feb 25.
ORIGINAL RESEARCH
Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B
Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3930-4. doi: 10.1073/pnas.0811844106. Epub 2009 Feb 23.
ORIGINAL RESEARCH
IGFBP3 colocalizes with and regulates hypocretin (orexin)
PLoS One. 2009;4(1):e4254. doi: 10.1371/journal.pone.0004254. Epub 2009 Jan 22.
ORIGINAL RESEARCH
Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity
Cell Metab. 2009 Jan 7;9(1):64-76. doi: 10.1016/j.cmet.2008.10.010.
ORIGINAL RESEARCH
New developments in sleep research: molecular genetics, gene expression, and systems neurobiology
J Neurosci. 2008 Nov 12;28(46):11814-8. doi: 10.1523/JNEUROSCI.3768-08.2008.
ORIGINAL RESEARCH
Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice
Eur J Neurosci. 2008 Oct;28(7):1382-93. doi: 10.1111/j.1460-9568.2008.06446.x.
ORIGINAL RESEARCH
Effect of neuropeptide B on feeding behavior is influenced by endogenous corticotropin-releasing factor activities
Regul Pept. 2008 Nov 29;151(1-3):147-52. doi: 10.1016/j.regpep.2008.08.001. Epub 2008 Sep 10.
ORIGINAL RESEARCH
Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy
Sleep. 2008 Aug;31(8):1119-26.
ORIGINAL RESEARCH
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia
J Clin Invest. 2008 Jul;118(7):2471-81. doi: 10.1172/JCI35115.
ORIGINAL RESEARCH
Cholinergic regulation of orexin/hypocretin neurons through M(3) muscarinic receptor in mice
J Pharmacol Sci. 2008 Mar;106(3):485-91. doi: 10.1254/jphs.fp0071986. Epub 2008 Mar 12.
ORIGINAL RESEARCH
Entrainment of temperature and activity rhythms to restricted feeding in orexin knock out mice
Brain Res. 2008 Apr 18;1205:47-54. doi: 10.1016/j.brainres.2008.02.026. Epub 2008 Feb 21.