PUBLICATIONS研究業績

Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states

Furutani N, Hondo M, Kageyama H, Tsujino N, Mieda M, Yanagisawa M, Shioda S, Sakurai T.

PLoS One. 2013 Apr 19;8(4):e62391. doi: 10.1371/journal.pone.0062391. Print 2013.

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Role of orexin in modulating arousal, feeding, and motivation

Tsujino N, Sakurai T.

Front Behav Neurosci. 2013 Apr 18;7:28. doi: 10.3389/fnbeh.2013.00028. eCollection 2013.

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Hypocretin/orexin neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice

Yang L, Zou B, Xiong X, Pascual C, Xie J, Malik A, Xie J, Sakurai T, Xie XS.

J Neurosci. 2013 Mar 20;33(12):5275-84. doi: 10.1523/JNEUROSCI.3200-12.2013.

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NPBWR1 and NPBWR2: Implications in Energy Homeostasis, Pain, and Emotion

Sakurai T.

Front Endocrinol (Lausanne). 2013 Mar 18;4:23. doi: 10.3389/fendo.2013.00023. eCollection 2013.

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Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice

Tsuneki H, Tokai E, Sugawara C, Wada T, Sakurai T, Sasaoka T.

Neuropeptides. 2013 Jun;47(3):213-9. doi: 10.1016/j.npep.2013.02.002. Epub 2013 Mar 16.

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Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status

Mieda M, Sakurai T.

CNS Drugs. 2013 Feb;27(2):83-90. doi: 10.1007/s40263-012-0036-8.

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Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation

Xiong X, White RE, Xu L, Yang L, Sun X, Zou B, Pascual C, Sakurai T, Giffard RG, Xie XS.

Stroke. 2013 Mar;44(3):764-70. doi: 10.1161/STROKEAHA.112.681700. Epub 2013 Jan 24.

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Optogenetic probing of fast glutamatergic transmission from hypocretin/orexin to histamine neurons in situ

Schöne C, Cao ZF, Apergis-Schoute J, Adamantidis A, Sakurai T, Burdakov D.

J Neurosci. 2012 Sep 5;32(36):12437-43. doi: 10.1523/JNEUROSCI.0706-12.2012.

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[Circadian rhythm of leptin, orexin and ghrelin]

Tsujino N, Sakurai T.

Nihon Rinsho. 2012 Jul;70(7):1121-5.

Overview of orexin/hypocretin system

Mieda M, Sakurai T.

Prog Brain Res. 2012;198:5-14. doi: 10.1016/B978-0-444-59489-1.00002-1.

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[Hypothalamic neuropeptides implicated in the regulation of sleep/wakefulness states]

Sakurai T.

Brain Nerve. 2012 Jun;64(6):629-37.

A single nucleotide polymorphism of the neuropeptide B/W receptor-1 gene influences the evaluation of facial expressions

Watanabe N, Wada M, Irukayama-Tomobe Y, Ogata Y, Tsujino N, Suzuki M, Furutani N, Sakurai T, Yamamoto M.

PLoS One. 2012;7(4):e35390. doi: 10.1371/journal.pone.0035390. Epub 2012 Apr 24.

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[Connectomics of orexin-producing neurons: analysis using mouse models]

Sakurai T.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2011 Nov;31(5-6):223-9.

Bmal1 in the nervous system is essential for normal adaptation of circadian locomotor activity and food intake to periodic feeding

Mieda M, Sakurai T.

J Neurosci. 2011 Oct 26;31(43):15391-6. doi: 10.1523/JNEUROSCI.2801-11.2011.

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Orexin neurons receive glycinergic innervations

Hondo M, Furutani N, Yamasaki M, Watanabe M, Sakurai T.

PLoS One. 2011;6(9):e25076. doi: 10.1371/journal.pone.0025076. Epub 2011 Sep 16.

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Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice

Sasaki K, Suzuki M, Mieda M, Tsujino N, Roth B, Sakurai T.

PLoS One. 2011;6(5):e20360. doi: 10.1371/journal.pone.0020360. Epub 2011 May 27.

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Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

Sakurai T, Mieda M.

Trends Pharmacol Sci. 2011 Aug;32(8):451-62. doi: 10.1016/j.tips.2011.03.007. Epub 2011 May 11.

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Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep

Mieda M, Hasegawa E, Kisanuki YY, Sinton CM, Yanagisawa M, Sakurai T.

J Neurosci. 2011 Apr 27;31(17):6518-26. doi: 10.1523/JNEUROSCI.6506-10.2011.

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Orexin gene transfer into zona incerta neurons suppresses muscle paralysis in narcoleptic mice

Liu M, Blanco-Centurion C, Konadhode R, Begum S, Pelluru D, Gerashchenko D, Sakurai T, Yanagisawa M, van den Pol AN, Shiromani PJ.

J Neurosci. 2011 Apr 20;31(16):6028-40. doi: 10.1523/JNEUROSCI.6069-10.2011.

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Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory

Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T.

PLoS One. 2011 Feb 24;6(2):e16972. doi: 10.1371/journal.pone.0016972.

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